PACSIN3

Across TCGA patient cohorts, PACSIN3 mutation is significantly associated with the RNA expression of many other genes, with 665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PACSIN3-associated genes across cancer lineages are RN7SKP205, MIR6068, and RNA5SP411. Each is linked with PACSIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PACSIN3-to-partner and partner-to-PACSIN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP205 grouped by PACSIN3-low versus PACSIN3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACSIN3→partner) and Y-score (partner→PACSIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SKP205 →	+0.175	+6.479	<.001	.001	3	2
SKCM	MIR6068 →	+0.738	+4.595	<.001	.004	3	2
UCEC	RNA5SP411 →	+1.162	+1.863	<.001	.003	3	2
UCEC	RNA5SP412 →	+0.452	+1.867	.001	.007	3	2
CESC	RN7SL447P →	+0.183	+5.201	<.001	.007	3	2
CESC	PDE2A-AS1 →	+0.095	+5.201	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 665 associations by consensus.

RN7SKP205 by PACSIN3 expression — LIHC

Explore this box plot interactively →