PACSIN3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PACSIN3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,863 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PACSIN3-associated genes across cancer lineages are ERC1, ACTN1, and RAB8B. Each is linked with PACSIN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PACSIN3-to-partner and partner-to-PACSIN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PACSIN3 versus ERC1 in LUNG_SCLC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACSIN3→partner) and Y-score (partner→PACSIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCERC1 →+1.169+1.084<.001<.00136
BREASTACTN1 →+1.242+1.182<.001.00535
STOMACHRAB8B →+2.195+1.800.003.00135
STOMACHSAMD12 →-2.304-1.274.005.00126
LUNG_SCLCSORBS3 →+1.406+0.764.007.00134
LUNG_SCLCMCCC2 →-0.899-0.911.002.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,863 associations by consensus.

PACSIN3 vs ERC1 — LUNG_SCLC

Per-sample scatter of PACSIN3 vs ERC1 in LUNG_SCLC (Pearson r = 0.61).

Explore this scatter interactively →

Exploration