PACSIN2

Across TCGA cell cohorts, PACSIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,159 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PACSIN2-associated GO terms across cancer lineages are Plasma membrane raft assembly, Caveola assembly, and Caveolin-mediated endocytosis. Each is linked with PACSIN2 in more than 16 cancer types. Because this analysis shows association rather than direction, both PACSIN2-to-partner and partner-to-PACSIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane raft assembly grouped by PACSIN2-low versus PACSIN2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PACSIN2→partner) and Y-score (partner→PACSIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Plasma membrane raft assembly →	+0.261	+0.866	<.001	<.001	3	17
LUNG_SCLC	Caveola assembly →	+0.242	+0.848	<.001	.002	3	17
LARGE_INTESTINE	Caveolin-mediated endocytosis →	+0.204	+1.007	<.001	<.001	3	15
LARGE_INTESTINE	Membrane raft assembly →	+0.212	+0.834	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Interleukin-34-mediated signaling pathway →	+0.155	+0.790	.004	.007	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.181	+1.183	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

Plasma membrane raft assembly by PACSIN2 expression — LUNG_SCLC

Explore this box plot interactively →