PACS2

Across TCGA patient cohorts, PACS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,818 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PACS2-associated proteins across cancer lineages are SEC23B, BAG5, and CDC42BPB. Each is linked with PACS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PACS2-to-partner and partner-to-PACS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PACS2 versus SEC23B in CCRCC, with a Pearson correlation of -0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PACS2→partner) and Y-score (partner→PACS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC23B →	-0.354	-0.430	<.001	<.001	3	7
LSCC	BAG5 →	+0.260	+0.442	<.001	<.001	3	7
BRCA	CDC42BPB →	+0.275	+0.511	<.001	.001	3	6
LSCC	CEP170B →	+0.354	+0.508	<.001	<.001	3	5
LSCC	CSDE1_S514 →	-0.936	-0.581	<.001	<.001	3	5
GBM	FKBP11 →	-0.517	-0.382	.003	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,818 associations by consensus.

PACS2 vs SEC23B — CCRCC

Explore this scatter interactively →