PACRGL

Across TCGA cell cohorts, PACRGL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,365 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PACRGL-associated GO terms across cancer lineages are Protein localization to cilium, Protein localization to non-motile cilium, and Microtubule organizing center organization. Each is linked with PACRGL in more than 16 cancer types. Because this analysis shows association rather than direction, both PACRGL-to-partner and partner-to-PACRGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by PACRGL-low versus PACRGL-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PACRGL→partner) and Y-score (partner→PACRGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to cilium →	+0.063	+0.910	<.001	<.001	3	17
BLOOD_Myeloma	Protein localization to non-motile cilium →	+0.077	+0.672	<.001	.007	2	16
PANCREAS	Microtubule organizing center organization →	+0.069	+0.766	<.001	.002	3	13
URINARY_TRACT	Intraciliary anterograde transport →	+0.099	+0.636	.001	.001	3	12
BREAST	Anaphase-promoting complex-dependent catabolic process →	+0.087	+0.788	.002	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization →	+0.121	+0.821	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,365 associations by consensus.

Protein localization to cilium by PACRGL expression — PANCREAS

Explore this box plot interactively →