PACRGL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PACRGL mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PACRGL-associated genes across cancer lineages are LRRC3C. Each is linked with PACRGL in more than 1 cancer types. Because this analysis shows association rather than direction, both PACRGL-to-partner and partner-to-PACRGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC3C grouped by PACRGL-low versus PACRGL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PACRGL→partner) and Y-score (partner→PACRGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELRRC3C →+0.395+3.777<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LRRC3C by PACRGL expression — LARGE_INTESTINE

Box plot of LRRC3C in PACRGL-low vs PACRGL-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration