Across TCGA pan-cancer cohorts, PACRG-AS2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of PACRG-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PACRG-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types PACRG-AS2 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where PACRG-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PACRG-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.006	.004	8	view →
KICH	All	All	+0.025	.013	4	view →
THCA	All	All	−0.007	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PACRG-AS2 RNA expression & survival · all PACRG-AS2 data types