PABPN1

Across TCGA cell cohorts, PABPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,177 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PABPN1-associated GO terms across cancer lineages are Endothelial to hematopoietic transition, Regulation of DNA repair, and Epigenetic regulation of gene expression. Each is linked with PABPN1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PABPN1-to-partner and partner-to-PABPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial to hematopoietic transition grouped by PABPN1-low versus PABPN1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPN1→partner) and Y-score (partner→PABPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Endothelial to hematopoietic transition →	+0.134	+0.905	<.001	<.001	3	17
SOFT_TISSUE	Regulation of DNA repair →	+0.065	+0.741	<.001	<.001	3	16
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.061	+0.784	<.001	<.001	3	16
LUNG_NSCLC_LUAD	Protein linear polyubiquitination →	+0.158	+0.647	<.001	<.001	3	16
PANCREAS	Chromosome condensation →	+0.137	+0.689	.001	.001	3	16
BONE	Constitutive heterochromatin formation →	+0.094	+0.637	.009	.003	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,177 associations by consensus.

Endothelial to hematopoietic transition by PABPN1 expression — SOFT_TISSUE

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