PABPC5

Across TCGA cell cohorts, PABPC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,555 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PABPC5-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions, Mitotic sister chromatid cohesion, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with PABPC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both PABPC5-to-partner and partner-to-PABPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions grouped by PABPC5-low versus PABPC5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC5→partner) and Y-score (partner→PABPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.061	+1.113	<.001	.001	3	6
OVARY	Mitotic sister chromatid cohesion →	+0.069	+0.358	.002	.003	3	5
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.062	+1.113	<.001	.001	3	5
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.062	+1.113	<.001	.001	3	5
SOFT_TISSUE	Spindle localization →	+0.076	+0.925	.002	.001	3	4
SOFT_TISSUE	Transcription initiation at RNA polymerase II promoter →	+0.051	+0.949	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,555 associations by consensus.

RNA splicing, via transesterification reactions by PABPC5 expression — SOFT_TISSUE

Explore this box plot interactively →