PABPC5

Across TCGA cell cohorts, PABPC5 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PABPC5-associated genes across cancer lineages are OR4F21, OR13D1, and OR56A1. Each is linked with PABPC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC5-to-partner and partner-to-PABPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F21 grouped by PABPC5-low versus PABPC5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC5→partner) and Y-score (partner→PABPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F21 →	+0.175	+3.141	<.001	.002	3	1
LARGE_INTESTINE	OR13D1 →	+0.032	+2.882	<.001	.005	3	1
LARGE_INTESTINE	OR56A1 →	+0.010	+2.882	.001	.005	3	1
LARGE_INTESTINE	FAM153B →	+0.487	+3.011	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.209	+2.688	.003	.008	3	1
LARGE_INTESTINE	KRTAP5-3 →	+0.038	+3.632	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

OR4F21 by PABPC5 expression — LARGE_INTESTINE

Explore this box plot interactively →