PABPC5-AS1

Across TCGA pan-cancer cohorts, PABPC5-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PABPC5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where PABPC5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PABPC5-AS1 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, UCEC, and KICH are the cancer types where PABPC5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PABPC5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.473	<.001	8	view →
UCEC	All	All	−0.344	<.001	6	view →
KICH	All	II,III,IV	−0.170	.006	6	view →
KIRC	All	II,III,IV	−0.114	.001	6	view →
KIRP	Female	II,III,IV	+0.387	.019	3	view →
HNSC	All	III,IV	+0.068	.009	2	view →
LIHC	All	All	+0.021	.026	2	view →
BRCA	Female	All	−0.075	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PABPC5-AS1–THCA

Open the THCA breakdown →