PABPC4

Across TCGA patient cohorts, PABPC4 mutation is significantly associated with the RNA expression of many other genes, with 887 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC4-associated genes across cancer lineages are EEF1A1P31, RNU6-179P, and RPL22P14. Each is linked with PABPC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PABPC4-to-partner and partner-to-PABPC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EEF1A1P31 grouped by PABPC4-low versus PABPC4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC4→partner) and Y-score (partner→PABPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EEF1A1P31 →	+0.130	+3.192	.007	.003	3	3
KIRP	RNU6-179P →	+0.396	+5.376	<.001	.005	3	2
KIRP	RPL22P14 →	+0.401	+5.060	<.001	.008	3	2
GBM	LINC02663 →	+0.128	+4.584	.004	.007	3	2
GBM	NDUFS5P4 →	+0.181	+4.203	.002	.008	3	2
SKCM	GEMIN2P2 →	+0.034	+2.560	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 887 associations by consensus.

EEF1A1P31 by PABPC4 expression — COAD

Explore this box plot interactively →