PABPC4

Across TCGA cell cohorts, PABPC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,991 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PABPC4-associated GO terms across cancer lineages are Ribosome biogenesis, rRNA processing, and Antigen processing and presentation of exogenous antigen. Each is linked with PABPC4 in more than 10 cancer types. Because this analysis shows association rather than direction, both PABPC4-to-partner and partner-to-PABPC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome biogenesis grouped by PABPC4-low versus PABPC4-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC4→partner) and Y-score (partner→PABPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Ribosome biogenesis →	+0.076	+0.553	<.001	<.001	3	11
BLOOD_Leukemia	rRNA processing →	+0.081	+0.582	<.001	<.001	3	11
SKIN	Antigen processing and presentation of exogenous antigen →	-0.157	-0.524	.001	<.001	3	11
BLOOD_Leukemia	rRNA metabolic process →	+0.075	+0.555	<.001	<.001	3	10
STOMACH	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.096	+0.763	<.001	.001	3	10
BONE	snRNA transcription by RNA polymerase III →	+0.058	+0.430	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,991 associations by consensus.

Ribosome biogenesis by PABPC4 expression — CNS

Explore this box plot interactively →