PABPC3

Across TCGA patient cohorts, PABPC3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,095 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PABPC3-associated genes across cancer lineages are ADRB2, MYBL2, and CLN5. Each is linked with PABPC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PABPC3-to-partner and partner-to-PABPC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PABPC3 versus ADRB2 in UCEC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC3→partner) and Y-score (partner→PABPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADRB2 →	-1.129	-0.500	.006	.003	3	4
LUAD	MYBL2 →	+1.484	+0.347	<.001	.001	3	3
UCEC	CLN5 →	-0.611	-0.360	.001	.005	3	3
BRCA	CPED1 →	-0.979	-0.472	<.001	.002	3	3
BRCA	GAB1 →	-0.812	-0.427	<.001	.001	3	3
CCRCC	C7 →	-1.703	-0.209	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,095 associations by consensus.

PABPC3 vs ADRB2 — UCEC

Explore this scatter interactively →