PABPC3

Across TCGA patient cohorts, PABPC3 mutation is significantly associated with the RNA expression of many other genes, with 2,281 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC3-associated genes across cancer lineages are ZFYVE19, PKP1, and RNF10P1. Each is linked with PABPC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PABPC3-to-partner and partner-to-PABPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZFYVE19 grouped by PABPC3-low versus PABPC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC3→partner) and Y-score (partner→PABPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZFYVE19 →	+0.249	+1.538	.008	.009	3	3
UCEC	PKP1 →	-0.693	-2.470	.002	.001	3	3
STAD	RNF10P1 →	+0.202	+2.694	.001	.007	3	3
UCEC	TXNL4A →	+0.282	+1.465	.003	.002	3	3
SKCM	HIRIP3 →	+0.405	+3.195	.003	.009	3	2
UCEC	THRB →	-0.515	-1.499	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,281 associations by consensus.

ZFYVE19 by PABPC3 expression — UCEC

Explore this box plot interactively →