PABPC3

Across TCGA cell cohorts, PABPC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,800 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PABPC3-associated GO terms across cancer lineages are Response to dehydroepiandrosterone, Transcription pausing by RNA polymerase II, and Positive regulation of RNA polymerase II transcription preinitiation complex assembly. Each is linked with PABPC3 in more than 10 cancer types. Because this analysis shows association rather than direction, both PABPC3-to-partner and partner-to-PABPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to dehydroepiandrosterone grouped by PABPC3-low versus PABPC3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC3→partner) and Y-score (partner→PABPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to dehydroepiandrosterone →	+0.178	+0.700	<.001	<.001	3	11
BONE	Transcription pausing by RNA polymerase II →	+0.193	+0.808	<.001	<.001	3	10
BONE	Positive regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.158	+0.555	<.001	<.001	3	10
PANCREAS	miRNA processing →	+0.081	+0.483	<.001	.002	2	10
BONE	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.137	+0.598	<.001	<.001	3	9
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.195	+0.446	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,800 associations by consensus.

Response to dehydroepiandrosterone by PABPC3 expression — BONE

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