Across TCGA pan-cancer cohorts, PABPC1P6 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PABPC1P6’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PABPC1P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PABPC1P6 is over-expressed in tumor.
HNSC are the cancer types where PABPC1P6 tumor–normal differential expression is most reproducible.