PABPC1P3

Across TCGA pan-cancer cohorts, PABPC1P3 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of PABPC1P3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PABPC1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PABPC1P3 is over-expressed in tumor.

KIRC, COAD, and LIHC are the cancer types where PABPC1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PABPC1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+0.711	<.001	12	view →
COAD	All	III,IV	+1.583	<.001	11	view →
LIHC	All	II,III,IV	+0.497	<.001	8	view →
HNSC	Male	All	+0.456	<.001	7	view →
KIRP	All	All	+0.422	.001	7	view →
BLCA	All	III,IV	+0.636	.001	6	view →
READ	All	All	+0.801	<.001	5	view →
CHOL	All	All	+1.083	<.001	3	view →
UCEC	All	All	+0.460	.044	2	view →
PRAD	All	All	+0.309	.002	2	view →
STAD	All	II,III,IV	+0.531	.032	1	view →
KICH	Male	II,III,IV	+0.431	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

PABPC1P3–KIRC

Open the KIRC breakdown →