PABPC1P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PABPC1P2 mutation is significantly associated with the RNA expression of many other genes, with 2,310 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1P2-associated genes across cancer lineages are VAT1, HMG20B, and MYO19. Each is linked with PABPC1P2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PABPC1P2-to-partner and partner-to-PABPC1P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1P2→partner) and Y-score (partner→PABPC1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMVAT1 →+0.651+3.369.009.00433
UCECHMG20B →+0.433+2.606.001.00533
UCECMYO19 →+0.416+2.070.002.00133
UCECEXOSC9 →+0.405+2.480.003<.00133
SKCMGOT1 →+0.621+3.369<.001.00432
UCECPLS3-AS1 →+0.180+2.678.007.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,310 associations by consensus.

Exploration