Across TCGA patient cohorts, PABPC1P2 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1P2-associated genes across cancer lineages are GAPDH, JNK_pT183_Y185, and VEGFR2. Each is linked with PABPC1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1P2-to-partner and partner-to-PABPC1P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1P2→partner) and Y-score (partner→PABPC1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GAPDH →	+1.114	+2.179	<.001	.035	3	2
UCEC	JNK_pT183_Y185 →	-0.176	-1.893	.009	.016	3	2
UCEC	VEGFR2 →	+0.343	+1.498	.004	.036	3	2
UCEC	4E-BP1_pT37_T46 →	-0.303	-1.906	.045	.016	3	2
LUSC	Rb_pS807_S811 →	+0.605	+2.179	.003	.035	2	2
LUSC	TAZ →	-0.184	-2.981	.007	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

PABPC1P2 survival (RNA) · tumor vs normal (RNA) · all PABPC1P2 data types