PABPC1P13

Across TCGA patient cohorts, PABPC1P13 RNA expression is significantly associated with the go_rna of many other GO terms, with 954 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PABPC1P13-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway by p53 class mediator, Negative regulation of DNA-templated DNA replication, and Negative regulation of transcription regulatory region DNA binding. Each is linked with PABPC1P13 in more than 2 cancer types. Because this analysis shows association rather than direction, both PABPC1P13-to-partner and partner-to-PABPC1P13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intrinsic apoptotic signaling pathway by p53 class mediator grouped by PABPC1P13-low versus PABPC1P13-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1P13→partner) and Y-score (partner→PABPC1P13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Regulation of intrinsic apoptotic signaling pathway by p53 class mediator →	+0.051	+0.002	<.001	<.001	3	2
THCA	Negative regulation of DNA-templated DNA replication →	+0.045	+0.003	<.001	.002	3	2
BRCA	Negative regulation of transcription regulatory region DNA binding →	+0.032	+0.001	.001	.006	3	2
COAD	Regulation of microtubule nucleation →	+0.033	+0.002	.002	.002	3	2
ESCA	RNA polymerase I preinitiation complex assembly →	+0.040	+0.011	.006	<.001	3	2
STAD	Microtubule polymerization or depolymerization →	+0.029	+0.009	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 954 associations by consensus.

Regulation of intrinsic apoptotic signaling pathway by p53 class mediator by PABPC1P13 expression — THCA

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