Across TCGA patient cohorts, PABPC1L2B mutation is significantly associated with the RNA expression of many other genes, with 498 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1L2B-associated genes across cancer lineages are RNU6-1140P, SYNGR1, and ACD. Each is linked with PABPC1L2B in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1L2B-to-partner and partner-to-PABPC1L2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L2B→partner) and Y-score (partner→PABPC1L2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-1140P →	+0.335	+5.219	.005	.006	3	2
UCEC	SYNGR1 →	-1.117	-3.459	<.001	.005	3	1
UCEC	ACD →	+0.563	+3.491	.003	.002	3	1
UCEC	CYB5B →	+0.863	+3.218	<.001	.009	3	1
UCEC	FUCA2 →	+0.557	+3.480	.002	.002	3	1
UCEC	KDM4C →	+0.459	+3.470	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 498 associations by consensus.

Exploration

PABPC1L2B survival (RNA) · tumor vs normal (RNA) · all PABPC1L2B data types