PABPC1L2B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PABPC1L2B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1L2B-associated genes across cancer lineages are Class-switched memory B-cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with PABPC1L2B in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1L2B-to-partner and partner-to-PABPC1L2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L2B→partner) and Y-score (partner→PABPC1L2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECClass-switched memory B-cells →-0.062-2.321.031.03611
UCECEndothelial cells →-0.039-2.279.043.03611
UCEClymphatic Endothelial cells →-0.025-2.268.038.03611
UCECmv Endothelial cells →-0.028-2.311.017.03611
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration