Across TCGA patient cohorts, PABPC1L2A mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1L2A-associated genes across cancer lineages are GAPDH, NF2, and p27_pT157. Each is linked with PABPC1L2A in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1L2A-to-partner and partner-to-PABPC1L2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L2A→partner) and Y-score (partner→PABPC1L2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.599	+3.169	.042	.020	3	1
UCEC	NF2 →	+0.269	+3.169	.023	.020	3	1
UCEC	p27_pT157 →	-0.081	-3.169	.010	.020	3	1
UCEC	Tuberin →	+0.409	+2.817	.005	.036	3	1
UCEC	Cyclin-D1 →	-0.182	-3.169	.040	.020	3	1
UCEC	Ku80 →	+0.380	+3.183	.003	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

PABPC1L2A survival (RNA) · tumor vs normal (RNA) · all PABPC1L2A data types