PABPC1L

Across TCGA patient cohorts, PABPC1L mutation is significantly associated with the RNA expression of many other genes, with 1,594 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PABPC1L-associated genes across cancer lineages are WWC2-AS1, CPT2, and TYW3. Each is linked with PABPC1L in more than 1 cancer types. Because this analysis shows association rather than direction, both PABPC1L-to-partner and partner-to-PABPC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WWC2-AS1 grouped by PABPC1L-low versus PABPC1L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L→partner) and Y-score (partner→PABPC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	WWC2-AS1 →	+0.126	+3.408	<.001	.009	3	2
UCEC	CPT2 →	+0.420	+2.329	.003	.003	3	2
UCEC	TYW3 →	+0.457	+1.895	<.001	.001	3	2
UCEC	ENTR1 →	+0.371	+3.021	.001	<.001	3	2
UCEC	NOLC1 →	+0.437	+2.243	.007	.005	3	2
UCEC	DHRS13 →	+0.534	+2.254	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,594 associations by consensus.

WWC2-AS1 by PABPC1L expression — SKCM

Explore this box plot interactively →