PABPC1L

Across TCGA cell cohorts, PABPC1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,809 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PABPC1L-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Pre-mRNA catabolic process, and Negative regulation of telomere maintenance. Each is linked with PABPC1L in more than 15 cancer types. Because this analysis shows association rather than direction, both PABPC1L-to-partner and partner-to-PABPC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by PABPC1L-low versus PABPC1L-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1L→partner) and Y-score (partner→PABPC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.120	+1.723	<.001	<.001	3	16
BONE	Pre-mRNA catabolic process →	+0.200	+1.279	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of telomere maintenance →	+0.084	+1.182	<.001	<.001	3	16
BONE	Viral translational termination-reinitiation →	+0.105	+1.784	<.001	<.001	3	16
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.104	-1.664	<.001	.002	3	15
OESOPHAGUS	Cilium-dependent cell motility →	-0.104	-1.664	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,809 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by PABPC1L expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →