PABPC1

Across TCGA cell cohorts, PABPC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,676 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PABPC1-associated GO terms across cancer lineages are Blastocyst growth, CUT catabolic process, and Negative regulation of protein localization to centrosome. Each is linked with PABPC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PABPC1-to-partner and partner-to-PABPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by PABPC1-low versus PABPC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PABPC1→partner) and Y-score (partner→PABPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Blastocyst growth →	+0.185	+0.946	<.001	.006	3	10
CNS	CUT catabolic process →	+0.096	+0.904	<.001	<.001	3	7
BONE	Negative regulation of protein localization to centrosome →	+0.127	+0.649	.003	.001	3	7
CNS	Formate biosynthetic process →	+0.119	+0.876	<.001	<.001	3	7
BLOOD_Lymphoma	ERBB2 signaling pathway →	+0.126	+0.698	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Folic acid metabolic process →	+0.115	+0.919	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,676 associations by consensus.

Blastocyst growth by PABPC1 expression — BLOOD_Myeloma

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