Across TCGA pan-cancer cohorts, PA2G4P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PA2G4P3’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where PA2G4P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PA2G4P3 is over-expressed in tumor.
STAD and COAD are the cancer types where PA2G4P3 tumor–normal differential expression is most reproducible.