PA2G4P1

Across TCGA pan-cancer cohorts, PA2G4P1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of PA2G4P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PA2G4P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PA2G4P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, KIRC, and LUAD are the cancer types where PA2G4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PA2G4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.397	<.001	10	view →
KIRC	All	All	+0.043	<.001	10	view →
LUAD	All	All	+0.088	.003	6	view →
LIHC	All	II,III,IV	+0.061	<.001	6	view →
STAD	Male	II,III,IV	+0.316	.001	4	view →
LUSC	All	All	+0.058	.002	4	view →
PRAD	All	All	+0.043	.041	2	view →
CHOL	Female	All	+0.110	.049	1	view →
BLCA	All	III,IV	+0.075	.022	1	view →
THCA	All	IV	−0.052	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

PA2G4P1–COAD

Open the COAD breakdown →