PA2G4

Across TCGA cell cohorts, PA2G4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,613 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PA2G4-associated GO terms across cancer lineages are rRNA metabolic process, Maturation of SSU-rRNA, and 'de novo' IMP biosynthetic process. Each is linked with PA2G4 in more than 18 cancer types. Because this analysis shows association rather than direction, both PA2G4-to-partner and partner-to-PA2G4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by PA2G4-low versus PA2G4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PA2G4→partner) and Y-score (partner→PA2G4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	rRNA metabolic process →	+0.111	+0.812	<.001	<.001	3	19
BONE	Maturation of SSU-rRNA →	+0.168	+1.265	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	'de novo' IMP biosynthetic process →	+0.183	+1.109	<.001	<.001	3	19
BONE	rRNA processing →	+0.118	+0.784	<.001	<.001	3	19
BONE	DNA replication checkpoint signaling →	+0.174	+0.729	<.001	<.001	3	19
BONE	Ribosomal small subunit biogenesis →	+0.117	+0.774	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,613 associations by consensus.

rRNA metabolic process by PA2G4 expression — BONE

Explore this box plot interactively →