P4HTM

Across TCGA cell cohorts, P4HTM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,645 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible P4HTM-associated GO terms across cancer lineages are Sperm motility, Flagellated sperm motility, and Cilium-dependent cell motility. Each is linked with P4HTM in more than 12 cancer types. Because this analysis shows association rather than direction, both P4HTM-to-partner and partner-to-P4HTM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by P4HTM-low versus P4HTM-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P4HTM→partner) and Y-score (partner→P4HTM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.100	-1.084	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.100	-1.084	.002	<.001	3	13
URINARY_TRACT	Cilium-dependent cell motility →	-0.080	-1.409	.005	<.001	3	11
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.080	-1.409	.005	<.001	3	11
URINARY_TRACT	Cilium movement involved in cell motility →	-0.087	-1.367	.001	.004	2	11
KIDNEY	ER-nucleus signaling pathway →	+0.109	+1.412	.004	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,645 associations by consensus.

Sperm motility by P4HTM expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →