P4HB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, P4HB protein abundance is significantly associated with the protein abundance of many other proteins, with 25,998 significant associations in total. GBM shows the largest number of these associations.

The most reproducible P4HB-associated proteins across cancer lineages are PPIB, HSPA5, and CRELD2. Each is linked with P4HB in more than 9 cancer types. Because this analysis shows association rather than direction, both P4HB-to-partner and partner-to-P4HB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P4HB→partner) and Y-score (partner→P4HB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPPIB →+0.490+0.631<.001<.001310
GBMHSPA5 →+0.500+0.629<.001<.001310
LUADCRELD2 →+0.536+0.396<.001<.001310
GBMSEC24D →+0.568+0.619<.001<.00139
GBMUGGT1 →+0.338+0.624<.001<.00139
GBMPPIC →+0.884+0.600<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 25,998 associations by consensus.

Exploration