P3H1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, P3H1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,850 significant associations in total. GBM shows the largest number of these associations.

The most reproducible P3H1-associated proteins across cancer lineages are PLOD1, THBS2, and RCN3. Each is linked with P3H1 in more than 8 cancer types. Because this analysis shows association rather than direction, both P3H1-to-partner and partner-to-P3H1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P3H1 versus PLOD1 in GBM, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P3H1→partner) and Y-score (partner→P3H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPLOD1 →+0.634+0.374<.001<.00139
CCRCCTHBS2 →+1.203+0.419<.001<.00139
GBMRCN3 →+0.848+0.372<.001<.00139
OVBMP1 →+1.107+1.216<.001<.00139
GBMIKBIP →+0.733+0.397<.001<.00139
GBMCOL5A1 →+0.738+0.402<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,850 associations by consensus.

P3H1 vs PLOD1 — GBM

Per-sample scatter of P3H1 vs PLOD1 in GBM (Pearson r = 0.63).

Explore this scatter interactively →

Exploration