P3H1

Across TCGA cell cohorts, P3H1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,070 significant associations in total. BONE shows the largest number of these associations.

The most reproducible P3H1-associated GO terms across cancer lineages are Regulation of mesenchymal stem cell proliferation, Positive regulation of mesenchymal stem cell proliferation, and Proteoglycan metabolic process. Each is linked with P3H1 in more than 16 cancer types. Because this analysis shows association rather than direction, both P3H1-to-partner and partner-to-P3H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mesenchymal stem cell proliferation grouped by P3H1-low versus P3H1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P3H1→partner) and Y-score (partner→P3H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of mesenchymal stem cell proliferation →	+0.234	+1.650	.001	<.001	3	17
BONE	Positive regulation of mesenchymal stem cell proliferation →	+0.234	+1.650	.001	<.001	3	17
BONE	Proteoglycan metabolic process →	+0.108	+1.303	.001	.006	3	16
BONE	Collagen fibril organization →	+0.299	+1.128	<.001	<.001	3	15
OESOPHAGUS	Ceramide metabolic process →	+0.087	+1.529	.001	.003	3	14
BONE	Vesicle cargo loading →	+0.120	+1.297	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,070 associations by consensus.

Regulation of mesenchymal stem cell proliferation by P3H1 expression — BONE

Explore this box plot interactively →