P2RY4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, P2RY4 mutation is significantly associated with the RNA expression of many other genes, with 2,947 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible P2RY4-associated genes across cancer lineages are EIF3JP1, RNA5SP321, and ECEL1P3. Each is linked with P2RY4 in more than 2 cancer types. Because this analysis shows association rather than direction, both P2RY4-to-partner and partner-to-P2RY4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY4→partner) and Y-score (partner→P2RY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEIF3JP1 →+0.167+2.105<.001<.00133
CESCRNA5SP321 →+0.329+5.539<.001.00432
LUSCECEL1P3 →+0.220+3.923<.001.00432
LUSCFGF7P1 →+0.112+4.906<.001.00332
LUSCMIR4767 →+0.644+3.846.001.00532
SKCMCCDC37-DT →+0.058+3.682<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,947 associations by consensus.

Exploration