P2RY2

Across TCGA patient cohorts, P2RY2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,410 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible P2RY2-associated genes across cancer lineages are ALDH3B2, GALNT5, and BICDL2. Each is linked with P2RY2 in more than 2 cancer types. Because this analysis shows association rather than direction, both P2RY2-to-partner and partner-to-P2RY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RY2 versus ALDH3B2 in LUAD, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY2→partner) and Y-score (partner→P2RY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ALDH3B2 →	+1.923	+0.713	<.001	<.001	3	3
UCEC	GALNT5 →	+2.032	+0.882	.007	.007	3	2
UCEC	BICDL2 →	+1.108	+1.073	.006	.001	3	2
UCEC	LAMA2 →	-1.472	-1.002	.004	.003	3	2
UCEC	OR8R1P →	+3.043	+1.533	<.001	<.001	2	3
LSCC	SGCG →	-0.780	-1.091	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,410 associations by consensus.

P2RY2 vs ALDH3B2 — LUAD

Explore this scatter interactively →