P2RY2

Across TCGA cell cohorts, P2RY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,694 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible P2RY2-associated GO terms across cancer lineages are Regulation of mucus secretion, T cell mediated cytotoxicity, and Skin development. Each is linked with P2RY2 in more than 17 cancer types. Because this analysis shows association rather than direction, both P2RY2-to-partner and partner-to-P2RY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mucus secretion grouped by P2RY2-low versus P2RY2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY2→partner) and Y-score (partner→P2RY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of mucus secretion →	+1.899	+2.618	<.001	<.001	3	18
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.237	+1.794	<.001	<.001	3	13
URINARY_TRACT	Skin development →	+0.134	+2.395	.001	<.001	3	11
OESOPHAGUS	Negative regulation of supramolecular fiber organization →	+0.074	+1.763	.005	.004	3	11
OESOPHAGUS	Regulation of actin filament polymerization →	+0.088	+2.212	<.001	<.001	3	11
BREAST	Epithelial cell-cell adhesion →	+0.160	+1.682	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,694 associations by consensus.

Regulation of mucus secretion by P2RY2 expression — PANCREAS

Explore this box plot interactively →