P2RY13

Across TCGA cell cohorts, P2RY13 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,042 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible P2RY13-associated GO terms across cancer lineages are Negative regulation of hippo signaling, Nuclear envelope organization, and Vacuole organization. Each is linked with P2RY13 in more than 3 cancer types. Because this analysis shows association rather than direction, both P2RY13-to-partner and partner-to-P2RY13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hippo signaling grouped by P2RY13-low versus P2RY13-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY13→partner) and Y-score (partner→P2RY13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of hippo signaling →	+0.060	+0.006	.008	.002	3	4
CNS	Nuclear envelope organization →	+0.042	+0.006	.006	.004	3	4
CNS	Vacuole organization →	+0.029	+0.007	.007	.002	3	4
URINARY_TRACT	Negative regulation of type I interferon production →	+0.051	+0.008	.002	.007	3	3
URINARY_TRACT	Regulation of stress fiber assembly →	+0.054	+0.008	.002	.007	3	3
SKIN	Serotonin transport →	+0.989	+0.002	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,042 associations by consensus.

Negative regulation of hippo signaling by P2RY13 expression — OVARY

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