P2RX6

Across TCGA patient cohorts, P2RX6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,153 significant associations in total. STAD shows the largest number of these associations.

The most reproducible P2RX6-associated GO terms across cancer lineages are Regulation of protein folding, Protein deacetylation, and Protein-containing complex disassembly. Each is linked with P2RX6 in more than 16 cancer types. Because this analysis shows association rather than direction, both P2RX6-to-partner and partner-to-P2RX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein folding grouped by P2RX6-low versus P2RX6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX6→partner) and Y-score (partner→P2RX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein folding →	+0.068	+0.203	<.001	<.001	3	17
STAD	Protein deacetylation →	+0.055	+0.178	<.001	<.001	3	17
STAD	Protein-containing complex disassembly →	+0.067	+0.199	<.001	<.001	3	17
STAD	Cytoskeleton-dependent intracellular transport →	+0.049	+0.163	<.001	<.001	3	17
ESCA	Glycolytic process through glucose-6-phosphate →	+0.064	+0.201	<.001	.002	2	17
STAD	Regulation of lipid biosynthetic process →	+0.043	+0.167	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,153 associations by consensus.

Regulation of protein folding by P2RX6 expression — STAD

Explore this box plot interactively →