P2RX5

Across TCGA patient cohorts, P2RX5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,282 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible P2RX5-associated genes across cancer lineages are TPTEP1, ZDHHC15, and STX1A. Each is linked with P2RX5 in more than 2 cancer types. Because this analysis shows association rather than direction, both P2RX5-to-partner and partner-to-P2RX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RX5 versus TPTEP1 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX5→partner) and Y-score (partner→P2RX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TPTEP1 →	+0.657	+0.588	.001	<.001	3	2
UCEC	ZDHHC15 →	+0.644	+0.417	.002	.006	3	2
GBM	STX1A →	-0.901	-0.863	<.001	.001	3	2
PDAC	BST1 →	+0.584	+0.516	<.001	.001	3	2
PDAC	CEP72 →	-0.401	-0.507	<.001	.001	3	2
LSCC	BCHE →	+2.585	+1.112	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,282 associations by consensus.

P2RX5 vs TPTEP1 — UCEC

Explore this scatter interactively →