P2RX5

Across TCGA patient cohorts, P2RX5 mutation is significantly associated with the RNA expression of many other genes, with 1,941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible P2RX5-associated genes across cancer lineages are RNU6-1318P, MIR4797, and UQCRH. Each is linked with P2RX5 in more than 2 cancer types. Because this analysis shows association rather than direction, both P2RX5-to-partner and partner-to-P2RX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by P2RX5-low versus P2RX5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX5→partner) and Y-score (partner→P2RX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1318P →	+0.420	+3.874	<.001	.006	3	3
LUAD	MIR4797 →	+0.550	+2.925	<.001	.008	3	3
SKCM	UQCRH →	+0.686	+3.465	<.001	.003	3	2
SKCM	PCBP1-AS1 →	+0.592	+3.182	<.001	.009	3	2
SKCM	THAP12P6 →	+0.049	+2.430	.001	.007	3	2
BRCA	MIR4255 →	+0.922	+8.055	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,941 associations by consensus.

RNU6-1318P by P2RX5 expression — CESC

Explore this box plot interactively →