P2RX5

Across TCGA cell cohorts, P2RX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,828 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible P2RX5-associated GO terms across cancer lineages are Osteoclast development, Bone cell development, and rRNA modification. Each is linked with P2RX5 in more than 16 cancer types. Because this analysis shows association rather than direction, both P2RX5-to-partner and partner-to-P2RX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoclast development grouped by P2RX5-low versus P2RX5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX5→partner) and Y-score (partner→P2RX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Osteoclast development →	-0.181	-2.493	<.001	<.001	3	17
BONE	Bone cell development →	-0.181	-2.493	<.001	<.001	3	17
BONE	rRNA modification →	+0.084	+1.523	.003	.006	2	10
BREAST	Regulation of cortisol secretion →	+1.453	+1.513	<.001	.001	3	9
BREAST	Positive regulation of cortisol secretion →	+1.453	+1.513	<.001	.001	3	9
SOFT_TISSUE	GMP biosynthetic process →	+0.075	+1.168	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,828 associations by consensus.

Osteoclast development by P2RX5 expression — BONE

Explore this box plot interactively →