OXTR

Across TCGA patient cohorts, OXTR protein abundance is significantly associated with the RNA expression of many other genes, with 486 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OXTR-associated genes across cancer lineages are SEC14L2, MCM5, and EMC9. Each is linked with OXTR in more than 1 cancer types. Because this analysis shows association rather than direction, both OXTR-to-partner and partner-to-OXTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OXTR versus SEC14L2 in GBM, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXTR→partner) and Y-score (partner→OXTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	+1.064	+1.207	<.001	<.001	3	1
GBM	MCM5 →	-0.653	-1.231	.002	<.001	3	1
GBM	EMC9 →	-0.544	-1.356	.008	.007	3	1
GBM	GINS1 →	-1.194	-1.686	<.001	<.001	3	1
GBM	E2F1 →	-0.912	-0.995	.001	.001	3	1
GBM	ACTR5 →	-0.470	-1.205	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 486 associations by consensus.

OXTR vs SEC14L2 — GBM

Explore this scatter interactively →