OXTR

Across TCGA cell cohorts, OXTR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,151 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OXTR-associated GO terms across cancer lineages are Regulation of systemic arterial blood pressure by vasopressin, Positive regulation of intracellular transport, and Wound healing. Each is linked with OXTR in more than 17 cancer types. Because this analysis shows association rather than direction, both OXTR-to-partner and partner-to-OXTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of systemic arterial blood pressure by vasopressin grouped by OXTR-low versus OXTR-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OXTR→partner) and Y-score (partner→OXTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of systemic arterial blood pressure by vasopressin →	+1.992	+4.053	<.001	<.001	3	18
BONE	Positive regulation of intracellular transport →	+0.086	+1.281	<.001	<.001	3	12
BONE	Wound healing →	+0.125	+0.932	.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.141	+1.366	<.001	.001	3	11
OVARY	Regulation of intracellular transport →	+0.059	+1.484	<.001	.001	3	11
STOMACH	Protein stabilization →	+0.065	+1.415	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,151 associations by consensus.

Regulation of systemic arterial blood pressure by vasopressin by OXTR expression — LIVER

Explore this box plot interactively →