OXTR

Across TCGA cell cohorts, OXTR mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OXTR-associated genes across cancer lineages are LY6G6F, PAX1, and KCNA10. Each is linked with OXTR in more than 1 cancer types. Because this analysis shows association rather than direction, both OXTR-to-partner and partner-to-OXTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY6G6F grouped by OXTR-low versus OXTR-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXTR→partner) and Y-score (partner→OXTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	1
BLOOD_Leukemia	PAX1 →	+0.053	+5.060	<.001	.001	3	1
BLOOD_Leukemia	KCNA10 →	+0.004	+4.539	.009	.007	3	1
BLOOD_Leukemia	DCD →	+0.024	+4.969	<.001	.003	3	1
BLOOD_Leukemia	MUC7 →	+0.215	+4.152	<.001	.009	3	1
BLOOD_Leukemia	RNASE11 →	+0.038	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

LY6G6F by OXTR expression — URINARY_TRACT

Explore this box plot interactively →