OXSR1

Across TCGA cell cohorts, OXSR1 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OXSR1-associated genes across cancer lineages are MTNR1B, GPR101, and CENPVL1. Each is linked with OXSR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXSR1-to-partner and partner-to-OXSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTNR1B grouped by OXSR1-low versus OXSR1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXSR1→partner) and Y-score (partner→OXSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MTNR1B →	+0.139	+4.906	<.001	.006	3	1
OESOPHAGUS	GPR101 →	+0.070	+4.906	<.001	.006	3	1
OESOPHAGUS	CENPVL1 →	+0.246	+4.906	<.001	.006	3	1
LARGE_INTESTINE	CR2 →	+0.993	+3.184	<.001	.007	3	1
LARGE_INTESTINE	NDUFB10 →	+0.557	+3.067	.001	.009	3	1
LARGE_INTESTINE	FCN2 →	+0.022	+3.415	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

MTNR1B by OXSR1 expression — OESOPHAGUS

Explore this box plot interactively →