OXSM

Across TCGA pan-cancer cohorts, OXSM mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OXSM data layer compared with 18 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OXSM mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated OXSM expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and HNSC are the cancer types where OXSM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.923	.018	54	view →
PDAC	OS	Tertile	III,IV	0.843	0.251	.008	15	view →
HNSC	DFS	Tertile	III,IV	0.818	0.536	.017	6	view →
OV	DFS	Median	All	1.000	0.811	.010	4	view →
CCRCC	DFS	Median	II,III,IV	0.408	0.773	.012	4	view →
LSCC	DFS	Median	All	0.721	0.858	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OXSM–COAD (DFS)

Open the COAD breakdown →