OXSM

Across TCGA cell cohorts, OXSM RNA expression is significantly associated with the go_rna of many other GO terms, with 3,341 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OXSM-associated GO terms across cancer lineages are tRNA 3'-terminal CCA addition, Mitochondrial tRNA 3'-end processing, and Short-chain fatty acid biosynthetic process. Each is linked with OXSM in more than 13 cancer types. Because this analysis shows association rather than direction, both OXSM-to-partner and partner-to-OXSM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 3'-terminal CCA addition grouped by OXSM-low versus OXSM-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OXSM→partner) and Y-score (partner→OXSM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	tRNA 3'-terminal CCA addition →	+0.135	+0.768	.003	.007	3	14
LIVER	Mitochondrial tRNA 3'-end processing →	+0.115	+0.397	.006	.007	3	12
LUNG_SCLC	Short-chain fatty acid biosynthetic process →	+0.746	+0.449	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial gene expression →	+0.078	+0.866	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	tRNA metabolic process →	+0.054	+0.724	<.001	.003	3	10
OESOPHAGUS	tRNA modification →	+0.056	+0.716	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

tRNA 3'-terminal CCA addition by OXSM expression — OESOPHAGUS

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