OXR1

Across TCGA pan-cancer cohorts, OXR1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated OXR1 data layer compared with 20 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher OXR1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OXR1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KICH, BRCA, and UCEC are the cancer types where OXR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.043	0.971	<.001	33	view →
BRCA	DFS	Median	All	0.140	1.000	.001	30	view →
UCEC	DFS	Median	All	0.921	0.614	.013	14	view →
PAAD	DFS	Median	All	0.100	0.484	.003	12	view →
LUSC	DFS	Median	III,IV	0.010	0.754	<.001	12	view →
SKCM	DFS	Median	All	0.411	0.764	.013	7	view →
SARC	OS	Median	All	0.186	0.595	.020	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OXR1–KICH (DFS)

Open the KICH breakdown →