OXR1

Across TCGA pan-cancer cohorts, OXR1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated OXR1 data layer compared with 20 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher OXR1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated OXR1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

PDAC, CCRCC, and COAD are the cancer types where OXR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.872	0.656	<.001	38	view →
CCRCC	OS	Tertile	III,IV	0.608	0.883	.021	17	view →
COAD	DFS	Median	IV	1.000	0.605	.043	6	view →
UCEC	DFS	Tertile	All	0.943	0.804	.047	2	view →
LSCC	DFS	Tertile	All	0.662	1.000	.030	2	view →
LUAD	OS	Tertile	III,IV	0.725	0.363	.035	2	view →
GBM	DFS	Median	All	0.844	0.648	.013	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OXR1–PDAC (DFS)

Open the PDAC breakdown →